This guide covers multidistrict litigation from the transfer motion through global settlement and remand. It begins with what the statute actually authorizes and the limits the transferee court operates under. It then covers the panel's factors, the choice of transferee district, tag-along practice, and direct filing with its choice of law consequences. Separate parts address leadership structures and how appointments are made, the case management orders that function as the operative law, fact sheets and census registries, common discovery and general causation, and the bellwether process with its waiver requirement. Later parts cover common benefit funds and their allocation, aggregate settlement and the ethical obligations it triggers, lien resolution, remand, the class action doctrine that defines the boundaries of the field, and the jurisdictional decisions that determine where cases can be brought. Each part states the rule, names the recurring failure, and gives the instruction.